[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511223":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":72,"collaborators":25,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":25,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":25,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":100,"whyStopped":25,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Tourniquet Group","EXPERIMENTAL","A temporary sub-placental uterine tourniquet will be temporarily applied before fetal extraction.",[13],"Procedure: A temporary sub-placental Uterine Tourniquet in management of Placenta Accreta Spectrum disorder by a retrograde cesarean hysterectomy (Bladder Last)",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-Tourniquet Group","No tourniquet will be used in this arm.",[18],"Procedure: Retrograde cesarean hysterectomy (Bladder Last) for management of Placenta Accreta Spectrum disorder",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","A temporary sub-placental Uterine Tourniquet in management of Placenta Accreta Spectrum disorder by a retrograde cesarean hysterectomy (Bladder Last)","Comparing the use of a temporary sub-placental uterine tourniquet versus no tourniquet in reducing blood loss in patients with Placenta Accreta Spectrum disorder undergoing cesarean hysterectomy.",[9],null,{"type":21,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"Retrograde cesarean hysterectomy (Bladder Last) for management of Placenta Accreta Spectrum disorder",[15],[30],{"name":31,"affiliation":32,"role":33},"Moutaz M Elsherbini, MD","Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt","STUDY_DIRECTOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Ahmed Eltawil, MSc","CONTACT","+201100009781","ahmed.eltawil512@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Abdalla Mousa, MD","+201277664430","dr_abdallamousa@yahoo.com",[45],{"facility":46,"status":47,"city":48,"state":25,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Research Ethics Committee, Faculty of Medicine, Cairo University","RECRUITING","Cairo","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.24967,30.06263,{"lat":55,"lon":54},[58,63,65,67,69,70],{"name":59,"role":37,"phone":60,"phoneExt":61,"email":62},"Ahmed Taha, Professor","01201730249","5012","kasralainyrec@kasralainy.edu.org",{"name":36,"role":64,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"name":66,"role":64,"phone":25,"phoneExt":25,"email":25},"Moutaz Elsherbini, MD",{"name":68,"role":64,"phone":25,"phoneExt":25,"email":25},"Rasha Elkomy, MD",{"name":41,"role":64,"phone":25,"phoneExt":25,"email":25},{"name":71,"role":64,"phone":25,"phoneExt":25,"email":25},"Mona Sediek, MD",{"type":64,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ahmed Eltawil","Teaching assistant","100511223","the-efficacy-of-a-temporary-sub-placental-uterine-tourniquet-in-minimizing-intraoperative-blood-loss-in-management-of-placenta-accreta-spectrum-disorder-by-a-retrograde-cesarean-hysterectomy-bladder-last-100511223",false,"NCT05936645","The Efficacy of a Temporary Sub-Placental Uterine Tourniquet in Minimizing Intraoperative Blood Loss in Management of Placenta Accreta Spectrum Disorder by a Retrograde Cesarean Hysterectomy (Bladder Last)","The Efficacy of a Temporary Sub-Placental Uterine Tourniquet in Minimizing Intraoperative Blood Loss in Management of Placenta Accreta Spectrum Disorder by a Retrograde Cesarean Hysterectomy (Bladder Last): A Prospective Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Gestational age: pregnancy completing 35 weeks or more.\n* Previous one or more cesarean delivery.\n* Current pregnancy complicated by Placenta Accreta Spectrum Disorder candidate for cesarean hysterectomy either total or partial Placenta Accreta. (i.e. Total: Most of the placenta is adherent to the myometrium with no plane of cleavage. Partial: 2-3 cotyledons are only adherent to the myometrium with no plane of cleavage at these cotyledons)\n* Elective termination of pregnancy.\n* Preoperative Hemoglobin ≥ 10 g\u002Fdl\n\nExclusion Criteria:\n\n* Patients who refuse to participate in the study.\n* Women with history of a concomitant chronic or a pregnancy associated medical disorder eg. Gestational diabetes, hypertension, cardiac or renal disease.\n* Presence of a concomitant uterine pathology (eg. Uterine fibroid)\n* Premature rupture of membranes.\n* Cases misdiagnosed as placenta accreta by ultrasound preoperatively, and spontaneous full placental separation occurred intraoperative or as total\u002Fpartial accreta and found to be focal accreta intraoperative.\n* Cases requiring preoperative blood transfusion.","FEMALE","20 Years","40 Years",{"count":86,"type":87},30,"ESTIMATED","INTERVENTIONAL",[90],"NA","This trial will study the role of a temporary tourniquet around the uterus to reduce blood loss in management of patients with abnormally implanted placenta who will undergo removal of the uterus.",[93],"Placenta Accreta",[95,96,97,98,99],"Placenta Accreta Spectrum","Tourniquet","Cesarean Hysterectomy","Bladder Last","Blood loss","UNKNOWN","2023-08-28",{"date":103,"type":104},"2023-08-30","ACTUAL",{"date":106,"type":104},"2023-08-01",{"date":108,"type":87},"2024-04-30",{"name":5,"class":6},1]