[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100192783":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":23,"locations":32,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Anemia Working Group Romania","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Dental treatment",null,"Assessment of the clinical state of the patient. Professional prophylaxis and removal of calculus. Extraction of hopeless teeth.Education of patient for oral hygiene. Periodic reevaluation.",[13],"Other: Dental treatment",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"1. The preliminary stage deals with:\n\n   * assessment of the clinical state of the patient by completing a detailed dental and periodontal chart\n   * education of the patient regarding correct oral hygiene habits;\n2. Phase I Therapy:\n\n   * plaque control : removal of dental plaque, calculus and root planning; antimicrobial therapy (local or systemic)\n   * evaluation of response to the treatment\n3. Phase II Therapy - surgical phase:\n\n   * extraction of hopeless teeth\n   * evaluation of the surgical results.\n4. Maintenance phase:\n\n   * periodic reevaluation of plaque and calculus and of periodontal conditions.",[9],[19],{"name":20,"affiliation":21,"role":22},"Oana Slusanschi, DMD","University of Medicine and Pharmacy Bucharest","PRINCIPAL_INVESTIGATOR",[24,28],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+40722266279","oanciu@yahoo.com",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":31},"Liliana Garneata, MD","+40722619358","lilianagarna@yahoo.com",[33],{"facility":34,"status":35,"city":36,"state":10,"zip":10,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"CMI \"Dr Slusanschi Oana\"","RECRUITING","Bucharest","Romania","RO",{"type":40,"coordinates":41},"Point",[42,43],26.10626,44.43225,{"lat":43,"lon":42},[46,47],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},{"name":20,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":22,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Oana Slusanschi","DMD","100192783","the-impact-of-periodontal-disease-treatment-on-the-general-health-status-in-chronic-haemodialyzed-patients-100192783",false,"NCT01785355","The Impact Of Periodontal Disease Treatment On The General Health Status In Chronic Haemodialyzed Patients","Periodontal Disease, Inflammation, Nutritional Status And Anaemia Response To Erythropoietin In Chronic Haemodialyzed Patients - The Impact Of Treatment For Periodontal Disease","PAROHEM","Inclusion Criteria:\n\n* Hemodialyzed patients with periodontal disease\n\nExclusion Criteria:\n\n* Malignancies, Diabetes\n* Patient refusal to participate","ALL","18 Years","85 Years",{"count":63,"type":64},30,"ESTIMATED","OBSERVATIONAL","Several studies revealed a direct relationship between the severity of periodontal inflammation and CRP (NHANES III, Dumitriu HT et al, 1998). In patients without any other source of inflammation but PDD, proper dental treatment of the disease decreased CRP to normal levels (Dumitriu H.T. et al., 1998; D'Aiuto F. et al, 2004; Borawski J. et al., 2007) Moreover, a direct link between high levels of CRP and atherosclerotic complications has been found in studies conducted both in general population (Ridker PM, et al., 1998; Koenig W, et al., 1999) and in HD subjects (Westhuyzen J, et al., 2000; Iseki K., et al., 1999; Zimmermann J, et al. 1998).",[68,69],"Periodontal Disease","Chronic Kidney Disease",[71,72,73,74,75,76,77],"periodontal disease","CKD","nutrition","inflammation","anemia response to ESA","quality of life","hemodialysis","UNKNOWN","2019-07-20",{"date":81,"type":82},"2019-07-23","ACTUAL",{"date":84,"type":82},"2012-09",{"date":86,"type":64},"2022-06",{"name":5,"class":6},1]