[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100192194":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":10,"locations":20,"responsibleParty":32,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":40,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"Damanhour University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"sulpiride 50 mg",null,[12],"Drug: Sulpiride",[14],{"type":15,"name":16,"description":10,"armGroupLabels":17,"otherNames":18},"DRUG","Sulpiride",[9],[19],"Dogmatil",[21],{"facility":22,"status":10,"city":23,"state":10,"zip":10,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":10},"Pharmaceutics Department, Faculty of Pharmacy, Damanhour University","Damanhur","Egypt","EG",{"type":27,"coordinates":28},"Point",[29,30],30.46823,31.03408,{"lat":30,"lon":29},{"type":33,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100192194","therapeutic-drug-monitoring-and-pharmacokinetic-compartmental-analysis-of-sulpiride-after-oral-administration-to-healthy-volunteers-100192194",false,"NCT01777685","Therapeutic Drug Monitoring and Pharmacokinetic Compartmental Analysis of Sulpiride After Oral Administration to Healthy Volunteers","Therapeutic Drug Monitoring and Pharmacokinetic Compartmental Analysis of Sulpiride","SUL","Inclusion Criteria:\n\n* At least 18 years old and not more than 45 healthy male volunteers\n* Actual weight no more than ± 30% from ideal body weight based on sex, height, and body frame\n* Who had passed all the screening parameters\n* Free of any drug exposure known to interfere with the pharmacokinetics or assay of sulpiride for at least 10 days prior to the study\n* Who had to be able to communicate effectively with study personnel, be literate, and able to give consent.\n\nExclusion Criteria:\n\n* A clinically significant abnormal physical exam, medical history, or laboratory studies If they showed a sitting SBP of \\>140 or \\\u003C100 mmHg, DBP \\> 90 or \\\u003C60mm Hg, or a pulse rate of \\> 95 or \\\u003C 50 beats\u002Fmin at screening A history of serious intolerance, allergy, or sensitivity to fexofenadine The use of any prescription drug within the previous month or use of any over-the-counter medication (with the exception of acetaminophen) within the past 14 days A history of blood dyscrasias A history of alcohol or drug abuse within the past year Donation of blood during the 8 weeks prior to the study or plans to donate blood during or within 8 weeks of completing the study Unable to tolerate vein puncture and multiple blood samplings Any surgical\u002Fmedical condition that might alter drug absorption, distribution, metabolism, or excretion Cannot follow instructions, in the opinion of the investigator.",true,"MALE","18 Years","45 Years",{"count":47,"type":48},16,"ACTUAL","INTERVENTIONAL",[51],"NA","The present study was adopted to evaluate the pharmacokinetics of sulpiride after oral administration.",[54],"Healthy",[16,56,57],"Therapeutic drug monitoring","Pharmacokinetics","COMPLETED","2013-01-28",{"date":61,"type":62},"2013-01-29","ESTIMATED",{"date":64,"type":10},"2013-01",{"date":64,"type":48},{"name":5,"class":6},1]