[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100509394":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":21,"locations":10,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":10},{"fullName":5,"class":6},"Tianjin Medical University General Hospital","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"BPS（Behavioral Pain Scale）and physiological index monitoring guided analgesia group",null,{"label":12,"type":10,"description":10,"interventionNames":13},"Analgesia group guided by qNOX",[14],"Device: qNOX",[16],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DEVICE","qNOX","Non",[12],[22,27],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Xiaohong Tang, MD","CONTACT","+8618522725286","tangxiaohong_txh@qq.com",{"name":28,"role":24,"phone":29,"phoneExt":10,"email":30},"Guolin Wang, MD","86-022-60362606","wang_guolin@hotmail.com",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Guolin Wang","Professor","100509394","to-investigate-the-impact-of-analgesic-management-guided-by-qnox-monitoring-on-the-comfort-and-prognosis-of-mechanically-ventilated-icu-patients-100509394",false,"NCT05912855","To Investigate the Impact of Analgesic Management Guided by qNOX Monitoring on the Comfort and Prognosis of Mechanically Ventilated ICU Patients","Inclusion Criteria:\n\n1. Patients aged 18 years or older who are undergoing abdominal, orthopedic, ENT（ear-nose-throat）, urological, neurosurgical or cardiothoracic surgery and require ICU treatment with mechanical ventilation while having an RASS（Richmond Agitation-Sedation Scale）-3 or -4 score;\n2. Patients unable to self-assess pain intensity using NRS（Numerical Pain Rating Scale）;\n3. Patients who have provided informed consent.\n\nExclusion Criteria:\n\n1. \\\u003C 18 years of age;\n2. Pregnant individuals;\n3. Patients with communication impairments, such as those who have experienced cerebrovascular accidents;\n4. A decision to withdraw life-sustaining treatment or an unstable medical condition that disrupts planned routine care.","ALL","18 Years","90 Years",{"count":45,"type":46},110,"ESTIMATED","OBSERVATIONAL","Purpose: To explore the effect of analgesic management under the guidance of qNOX monitoring on the comfort level and prognosis of patients with mechanical ventilation in ICU.\n\nMethod:After admission to ICU, the patients were randomly divided into the analgesia group guided by BPS（Behavioral Pain Scale） and physiological indicators monitoring and qNOX-guided analgesia group (qNOX group). Sedation and analgesia program after admission to ICU (continuous injection pump) : propofol 1.5-4.5mg\u002Fkg.h, remifentanil 5-8ug\u002Fkg.h, maintain sedation goals RASS（Richmond Agitation-Sedation Scale）-3 to -4 scores, BPS（Behavioral Pain Scale）3 to 4 scores. The researchers worked with the bedside nurse to plan different care procedures, including :1) central venous catheter or arterial catheter puncture; 2) The patient is turned over completely so that the back can be washed and the sheets changed; 3) Endotracheal sputum aspiration (patients with intubation or in tracheotomy state ); 4) Dressing the wound.\n\nPrimary outcome:Value of qNOX at BPS（Behavioral Pain Scale）≥5 (qNOX sensitivity, specificity, positive predictive value and negative predictive value) Secondary outcome:To investigate the patient baseline variables that may affect qNOX; Variables that may influence qNOX in relation to critical illness.",[50],"Pain","UNKNOWN","2023-06-24",{"date":54,"type":55},"2023-06-27","ACTUAL",{"date":57,"type":46},"2023-06",{"date":59,"type":46},"2024-10",{"name":5,"class":6}]