[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100272551":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":29,"locations":38,"responsibleParty":51,"collaborators":28,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":28,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":28,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":28,"overallStatus":73,"whyStopped":28,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Mahidol University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TDF\u002F3TC or FTC\u002FEFV plus Calcium and vitamin D supplement","ACTIVE_COMPARATOR","Once daily calcium carbonate 1,250 mg that equal to elemental calcium 600 mg and weekly vitamin D2 20,000international units are given in intervention arms for duration of 24 weeks the subjects in this arm continue previous ART before enrollment to the study",[13],"Drug: TDF\u002F3TC or FTC\u002FEFV plus Calcium and vitamin D supplement",{"label":15,"type":6,"description":16,"interventionNames":17},"TDF\u002F3TC or FTC\u002FEFV","the subjects in this arm continue previous ART before enrollment to study without any intervention with standard for HIV-infected patient.",[18],"Other: TDF\u002F3TC or FTC\u002FEFV",[20,25],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"DRUG",[9],[24],"ergocalciferol",{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":28},"arm continue previous ART before enrollment to study without any intervention with standard for HIV-infected patient.",[15],null,[30,35],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Patawee Boontanondha, M.D.","CONTACT","669-1774-6012","pataweeb44@gmail.com",{"name":36,"role":32,"phone":37,"phoneExt":28,"email":28},"Sasisopin Kiertiburanakul, M.D.MHS","662-201-0033",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":28,"geoPoint":28,"contacts":47},"Patawee Boontanondha","RECRUITING","Faculty of Medicine Ramathibodi Hospital, Mahidol University","Bangkok","10400","Thailand","TH",[48,49],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},{"name":50,"role":32,"phone":37,"phoneExt":28,"email":28},"Sasisopin Sasisopin Kiertiburanakul, MD, MHS",{"type":52,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100272551","vitamin-d-and-calcium-supplement-attenuate-bone-loss-among-hiv--infected-patients-receiving-tenofovir-disoproxil-fumarate-lamivudine-or-emtricitabine-and-efavirenz-100272551",false,"NCT02827643","Vitamin D and Calcium Supplement Attenuate Bone Loss Among HIV- Infected Patients Receiving Tenofovir Disoproxil Fumarate, Lamivudine or Emtricitabine and Efavirenz","Vitamin D and Calcium Supplement Attenuate Bone Loss Among HIV- Infected Patients Receiving Tenofovir Disoproxil Fumarate, Lamivudine or Emtricitabine and Efavirenz: An Open-label, Randomized Controlled Trial","Inclusion Criteria:\n\n* HIV-1-infected patients who start 3TC or FTC,TDF and EFV within 3 months before enrollment\n* Age 18-50 years\n\nExclusion Criteria:\n\n* CrCl \\\u003C60mL\u002Fmin\u002F1.73 m2 ¶-\n* CaCO3 supplement \\>500 mg\u002Fday or vitamin D supplement \\>800 IU\u002Fday\n* Steroid used (equivalent to prednisolone\\> 5 mg\u002Fday more than 3 months )\n* Osteoporosis treatment\n* Serum Ca \\>10.5 g\u002FdL\n* History fragility fracture\n* Pregnancy or breastfeeding\n* Secondary amenorrhea\n* Hyperthyroidism\n* History of kidney stone\n* Current active opportunistic infection",true,"ALL","18 Years","50 Years",{"count":65,"type":66},48,"ESTIMATED","INTERVENTIONAL",[69],"NA","The purpose of this study is to determine whether calcium and vitamin D supplement can attenuate bone loss in HIV-infected-patients in Thailand who receive Tenofovir disoproxil fumarate.",[72],"Bone Density","UNKNOWN","2016-07-07",{"date":76,"type":66},"2016-07-11",{"date":78,"type":28},"2016-06",{"date":80,"type":66},"2017-06",{"name":5,"class":6},1]