[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Laura Ozer Kettner\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100652017","oral-immunotherapy-for-children-with-cows-milk-allergy-100652017",false,"NCT07768696","Oral Immunotherapy for Children With Cow's Milk Allergy","Oral Immunotherapy for Children With Cow's Milk Allergy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 6 to 18 months\n* Cow's milk allergy confirmed at an oral food challenge\n* Reaction threshold below 300 mg of cow's milk protein at the oral food challenge\n* Specific IgE to cow's milk \\> 0.35 kU\u002FL\n* High risk of persistent allergy to cow's milk (based on defined criteria)\n* Family motivated for oral immunotherapy following shared decision-making using a decision aid\n\nExclusion Criteria:\n\n* Uncontrolled asthma, eczema, rhino-conjunctivitis, urticaria, or eosinophilic esophagitis\n* Treatment with biologic or immunosuppressive medication\n* Non-Danish-speaking families\n* Anticipated non-adherent families","ALL","6 Months","18 Months",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","This clinical trial aims to investigate if oral immunotherapy can help children with cow's milk allergy tolerate cow's milk.\n\nChildren aged 6-18 months can take part in the trial.\n\nMain question: What percentage of children can tolerate cow's milk after oral immunotherapy, compared with children who avoid cow's milk?\n\nChildren are assigned to these two groups by chance.\n\nChildren receiving oral immunotherapy will:\n\n* Take a small, increasing amount of cow's milk daily for 1-1.5 years\n* Attend clinic or online visits each time the dose is increased\n* Record missed doses\n\nAll children will:\n\n* Provide blood samples to measure allergy-related markers\n* Undergo an oral food challenge with cow's milk after 1-1.5 years to assess how much they can tolerate\n* Report allergic reactions (parent-reported)\n* Complete questionnaires (parent-reported)\n* Participate in an end-of-study telephone interview with an allergy nurse (parent-reported)",[27,28,29],"Milk Allergy, Cow's","Food Allergy in Children","Food Allergies",[31,32,33],"Oral immunotherapy","OIT","Desensitization","NOT_YET_RECRUITING","2026-08-12",{"date":37,"type":38},"2026-08-17","ACTUAL",{"date":40,"type":21},"2026-09",{"date":42,"type":21},"2031-09",{"name":44,"class":45},"Laura Ozer Kettner","OTHER",5,""]