[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Peter Hendricks\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100652350","phase-2-psilocybin-for-methamphetamine-use-disorder-100652350",false,"NCT07774702","Psilocybin for Methamphetamine Use Disorder","Psilocybin in the Treatment of Methamphetamine Use Disorder","Inclusion Criteria:\n\n* Age 18+\n* DSM-5 moderate or severe Methamphetamine Use Disorder\n* Severity of Dependence Scale score ≥ 4\n* Methamphetamine use on more than 7 of the past 30 days and more than one positive urine test before randomization\n* A goal of complete abstinence on the Thoughts About Abstinence questionnaire\n* Able to read, write, and speak English\n* A friend or family member available for post-session release\n* Good general health by history and physical\n* Confirmed pre-dose abstinence of at least 24 hours (clinically assessed)\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding, or not using effective contraception\n* Current psychiatric diagnoses other than a mild substance use disorder or tobacco\u002Fnicotine use disorder\n* Current hypertension (\\>140\u002F90 at rest)\n* Regular use of centrally acting serotonergic medications or MAO inhibitors (washout\u002Fre-screen permitted)\n* Personal history of any psychotic or bipolar I\u002FII disorder, or a first- or second-degree relative with such\n* Current suicidal or homicidal ideation\n* Plan to relocate within 6 months\n* Psychedelic use in the past 3 years, more than 3 lifetime psychedelic occasions, more than 3 lifetime ketamine or MDMA occasions, or any prior 5-MeO-DMT or ibogaine use","ALL","18 Years",{"count":19,"type":20},42,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","This trial tests whether psilocybin-assisted treatment can help adults stop using methamphetamine. Participants receive a single oral dose of psilocybin during a supervised session, paired with brief cognitive behavioral therapy, and are followed for up to six months. The study is supported by the HEAL Initiative (https:\u002F\u002Fwww.nih.gov\u002Fheal).",[26],"Methamphetamine Use Disorder",[28,29,30,31,32],"psilocybin","methamphetamine","HEAL Initiative","psychedelic-assisted therapy","substance use disorder","NOT_YET_RECRUITING","2026-08-17",{"date":36,"type":37},"2026-08-19","ACTUAL",{"date":39,"type":20},"2027-02-01",{"date":41,"type":20},"2032-02-01",{"name":43,"class":44},"Peter Hendricks","OTHER",""]