[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Xin Lou\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":118},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,73,100],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100651627","this-prospective-observational-study-aims-to-evaluate-the-capability-of-ultra-high-resolution-photon-counting-ct-angiography-uhr-pcd-cta-for-noninvasive-evaluation-of-intracranial-venous-sinus-stents-the-study-will-compare-image-quality-stent-visualization-metal-related-artifacts-and-diagnosti-100651627",false,"NCT07762677","This Prospective Observational Study Aims to Evaluate the Capability of Ultra-high-resolution Photon-counting CT Angiography (UHR PCD-CTA) for Noninvasive Evaluation of Intracranial Venous Sinus Stents. The Study Will Compare Image Quality, Stent Visualization, Metal-related Artifacts, and Diagnosti","Evaluation of Ultra-High-Resolution Photon-Counting CT Angiography for Intracranial Venous Sinus Stent Assessment","Inclusion Criteria:\n\n* Adults aged ≥18 years.\n* History of intracranial venous sinus stent implantation.\n* Undergoing follow-up contrast-enhanced CT angiography after stent -placement.\n* Available clinical and imaging data.\n\nExclusion Criteria:\n\n* Severe motion artifacts affecting image interpretation.\n* Contraindication to iodinated contrast media.\n* Severe renal impairment preventing contrast-enhanced CT examination.\n* Incomplete imaging data.\n* Other conditions preventing reliable assessment of the venous sinus stent.","ALL","18 Years","90 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the effectiveness of ultra-high-resolution photon-counting CT angiography (UHR PCD-CTA) for noninvasive assessment of intracranial venous sinus stents. The study will compare image quality, stent visualization, metal-related artifacts, and diagnostic accuracy between PCD-CTA and conventional energy-integrating detector CT angiography (EID-CTA).",[25,26,27,28,29],"Intracranial Stenosis","Venous Sinus Stenosis","Stent Implantation","Intracranial Venous Pressures","Intracranial Venous Sinus Stenosis",[31,32,33,34],"Photon-counting CT","Intracranial venous sinus stent","Ultra-high-resolution CT","CT angiography","RECRUITING","2026-08-19",{"date":38,"type":39},"2026-08-20","ACTUAL",{"date":41,"type":39},"2026-01-07",{"date":43,"type":21},"2029-01-07",{"name":45,"class":46},"Xin Lou","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":18,"enrollmentInfo":56,"targetDuration":57,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":72,"locationsCount":47},"100652127","photon-counting-ct-for-intracranial-stent-assessment-100652127","NCT07769814","Photon-counting CT for Intracranial Stent Assessment","Evaluation of Ultra-high Resolution Photon-counting CT Angiography for Intracranial Stent Assessment: A Prospective Diagnostic Study With Digital Subtraction Angiography as Reference Standard","Inclusion Criteria:\n\n1. Age ≥18 years;\n2. Patients with previously implanted intracranial arterial stents;\n3. Undergoing follow-up CTA examination;\n4. Available imaging data for analysis.\n\nExclusion Criteria:\n\n1. Severe motion artifacts;\n2. Poor contrast enhancement;\n3. Incomplete clinical or imaging data.","5 Years",{"count":20,"type":21},"4 Years","Intracranial atherosclerotic disease is an important cause of ischemic stroke, and intracranial stent implantation is increasingly used for patients with severe stenotic lesions. Evaluation of stent patency and detection of in-stent restenosis are essential during follow-up. Digital subtraction angiography (DSA) remains the reference standard for intracranial stent assessment; however, it is an invasive procedure associated with potential complications and radiation exposure. Conventional CT angiography may be limited by stent-related artifacts, including blooming artifact and beam-hardening effects, which can impair accurate evaluation of the stent lumen.",[60,61,62,63],"Intracranial Atherosclerotic Disease (ICAD)","Intracranial Arterial Stenosis","Stent Restenosis","Ischemic Stroke",[31,33,65,66,34],"In-stent restenosis","Intracranial stent","2026-08-12",{"date":69,"type":39},"2026-08-18",{"date":41,"type":39},{"date":43,"type":21},{"name":45,"class":46},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":83,"studyType":22,"phases":4,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":47},"100584524","three-in-one-stop-computed-topography-angiographycta-and-ct-perfusionctp-in-cerebrovascular-disease-100584524","NCT06890468","Three-in-One Stop Computed Topography Angiography(CTA) and CT Perfusion(CTP) in Cerebrovascular Disease","Three-in-One Stop Computed Topography Angiography and CT Perfusion in Cerebrovascular Disease","Inclusion Criteria:\n\n* Age≥18 \\\u003C100years\n* Head and neck artery stenosis\u002Focclusion, moyamoya disease, aneurysm, artery dissection, etc., may include patients with acute stroke, chronic cerebral ischemia, and asymptomatic patients. After clinical assessment, CT perfusion imaging is required\n* The image quality meets the requirements of diagnosis and post-processing\n* Patients who follow the scanning strategy to complete the examination\n* The patient or his or her family agrees to provide clinical data and follow-up\n* Patients or their families sign informed consent forms\n\nExclusion Criteria:\n\n* \\\u003C 18 years old\n* People who are allergic to iodine contrast agents, or who cannot be tested temporarily due to taking metformin or aminoglycoside drugs\n* Renal failure patient\n* Severe cardiac insufficiency\n* Severe liver damage\n* Patients with an expected survival of less than 1 year\n* Patients with cerebrovascular diseasePregnant woman","100 Years",{"count":82,"type":21},1000,"1 Year","This research takes patients with cerebrovascular diseases as the research subjects and employs the experimental design of a prospective cohort study, aiming to innovatively develop and validate a \"one-stop\" multimodal CT examination scheme. The 301-CTAP multimodal CT technique implies that three modalities are acquired through a single collection, including head and neck CTA (head and neck CTA), multiphase CTA imaging of the brain (multiphase CTA), and CT perfusion imaging of the brain (CT perfusion).",[86,87],"Radiology","Vascular Diseases",[89,90],"CTP","head and neck CTA","NOT_YET_RECRUITING","2025-03-21",{"date":94,"type":39},"2025-03-24",{"date":96,"type":21},"2025-03-16",{"date":98,"type":21},"2029-12-30",{"name":45,"class":46},{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":108,"conditions":109,"keywords":4,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":4},"100561413","artificial-intelligent-image-processing-and-diagnosis-of-pulmonary-vessels-in-ct-100561413","NCT06589843","Artificial Intelligent Image Processing and Diagnosis of Pulmonary Vessels in CT","Inclusion Criteria:\n\n* Age ≥18≤100 years old Scan the pulmonary artery and its major branches Patients with suspected pulmonary embolism who received CTPA had a set of CTPA and CT scans The image quality meets the requirements of diagnosis and post-processing Patients who completed the examination in accordance with the data collection criteria Clinical data and follow-up were complete\n\nExclusion Criteria:\n\n* Age \\<18 years or age \\>100 years The image is incomplete or incorrect Pulmonary artery absent or underenhanced Severe motion artifacts or image noise affect evaluation of pulmonary embolism History of aortic reconstruction, replacement, or stent implantation Congenital variations in the whole or important branches of the aorta in adults (e.g. bovine aortic arch, abnormal right subclavian artery) Severe hypovolemia and hemodynamic instability Severe heart failure with low ejection fraction Dialysis patient",{"count":107,"type":21},15000,"In this study, patients with chest pain, lung cancer, pulmonary embolism, and routine inpatient physical examination were selected as the research objects, and the experimental design of retrospective cohort study was adopted to carry out artificial intelligence analysis related to pulmonary vascular diseases in patients with multi-dimensional big data. The multi-modal CT acquisition process included plain scan CT(NCCT) and CT pulmonary angiography (CTPA). Ctpa-like image effects can be simulated or reconstructed by non-enhanced plain scan CT images, so that CTPA-like image quality can be obtained without injecting contrast agent. The synthetic CTPA images were further analyzed by artificial intelligence to assist doctors in the intelligent diagnosis of pulmonary vascular diseases.",[86,87],"2024-09-06",{"date":112,"type":39},"2024-09-19",{"date":114,"type":21},"2024-09-10",{"date":116,"type":21},"2029-09-01",{"name":45,"class":46},""]